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Peer-reviewed publications

(*denotes students, postdocs and research assistants)


Panlilio JM*, Jones IT, Salanga MC, Aluru N, Hahn, ME. Developmental exposure to domoic acid disrupts startle response behavior and circuitry in zebrafish. Toxicol Sci. 2021. kfab066, [Epub ahead of print]

Pandelides Z*, Aluru N, Thornton C, Watts HE, Willett KL. Transcriptomic Changes and the Roles of Cannabinoid Receptors and PPARγ in Developmental Toxicities Following Exposure to Δ9-Tetrahydrocannabinol and Cannabidiol. Toxicol Sci. 2021 Apr 21;. doi: 10.1093/toxsci/kfab046. [Epub ahead of print]

Aluru N, G Hallanger I, McMonagle H*, Harju M. Hepatic Gene Expression Profiling of Atlantic Cod (Gadus morhua) Liver after Exposure to Organophosphate Flame Retardants Revealed Altered Cholesterol Biosynthesis and Lipid Metabolism. Environ Toxicol Chem. 2021 Jun;40(6):1639-1648.


Aluru N, Karchner SI. PCB126 Exposure Revealed Alterations in m6A RNA Modifications in Transcripts Associated With AHR Activation. Toxicol Sci. 2021 Jan 6;179(1):84-94.

Panlilio JM*, Aluru N, Hahn ME. Developmental Neurotoxicity of the Harmful Algal Bloom Toxin Domoic Acid: Cellular and Molecular Mechanisms Underlying Altered Behavior in the Zebrafish Model. Environ Health Perspect. 2020 Nov;128(11):117002.

Aluru N, Krick KS*, McDonald AM*, Karchner SI. Developmental Exposure to PCB153 (2,2',4,4',5,5'-Hexachlorobiphenyl) Alters Circadian Rhythms and the Expression of Clock and Metabolic Genes. Toxicol Sci. 2020 Jan 1;173(1):41-52.


Xu, X.,  Li, G., Li, C., Zhang, J., Wang, Q., Simmons, D.K., Chen, X., Wijesena, N., Zhu, W., Wang, Z., Wang, Z., Ju, B., Ci, W., Lu, X., Yu, D., Wang, Q.,  Aluru, N., Oliveri, P., Zhang, Y.E., Martindale, M.Q., Liu, J. 2019. Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis. National Science Review nwz064, :


Glazer, L*., Kido Soule, M.C., Longnecker, K., Kujawinski, E.B., Aluru, N. 2018 Hepatic metabolite profiling of polychlorinated biphenyl (PCB)-resistant and sensitive populations of Atlantic killifish (Fundulus heteroclitus). Aquatic Toxicology. 205:114-122.

Oh, D.-J., Hur, S.-P., Bouchekioua, S., Takeuchi, Y., Udagawa, S., Aluru, N., Park, Y-J., Park, Ji-G., Kim, Se-J., Moon, T.W., Vijayan, M.M., Takemura, A. 2018. Tide-related changes in mRNA abundance of aromatases and estrogen receptors in the ovary and brain of the Three spot Wrasse Halichoeres trimaculatusOcean Science Journal. 53(2), 239-249.

Aluru, N., Karchner, S.I., Krick, K.S*., Zhu, W., Liu, J. 2018. Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3′, 4, 4′, 5-pentachlorobiphenyl (PCB 126). Environmental Epigenetics. 4(1):dvy005.

Sadoul, B., Birceanu, O., Aluru, N., Thomas, J.K. Vijayan, M.M. 2017. Bisphenol A in eggs causes development-specific liver molecular reprogramming in two generations of rainbow trout. Scientific Reports7(1):14131.


Aluru, N., Karchner, S.I., Glazer, L*. 2017. Early life exposure to low levels of AHR agonist PCB126 (3,3’,4,4’,5-pentachlorobiphenyl) reprograms gene expression in adult brain. Toxicological Sciences (

Aluru, N. 2017. Epigenetic effects of environmental chemicals: Insights from zebrafish. Critical Reviews in Toxicology, 6: 27-33.

Sadoul, B., Birceanu, O., Aluru, N., Thomas, J.K. Vijayan, M.M. 2017. Bisphenol A in eggs causes development-specific liver molecular reprogramming in two generations of rainbow trout. Scientific Reports  7: 14131.

Reid, N.M., Jackson, C.E., Gilbert, D., Minx, P., Montague, M.J., Hampton, T.H., Helfrich, L.W*., King, B.L., Nacci, D.E., Aluru, N., Karchner, S.I., Colbourne, J.K., Hahn, M.E., Shaw, J.R., Oleksiak, M.F., Crawford, D.L., Warren, W.C., Whitehead, A. 2017. The landscape of extreme genomic variation in the highly adaptable Atlantic killifish. Genome Biology and Evolution, 9 (3): 659–676.


Faught, E., N. Aluru, M.M. Vijayan. 2016. Chapter 4. The molecular stress response. In: Fish Physiology, Volume 35. Biology of Stress in Fish. Eds. C.B. Shreck, L. Tort, A. Farrell, C. Brauner. Academic Press.

Glazer, L*., Hahn, M.E., Aluru, N. 2016. Delayed effects of developmental exposure to low levels of the aryl hydrocarbon receptor agonist 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) on adult zebrafish behavior. Neurotoxicology, 52: 134-143.


Lopes-Marques, M., R. Ruivo, I. Delgado, J.M. Wilson, N. Aluru, and L.F. Castro. 2015. Basal Gnathostomes provide unique insights into the evolution of vitamin B12 bindersGenome Biol Evol7(2): 457-464.

Aluru, N., Kuo, E*., Helfrich, L.W*., Karchner, S.I., Linney, E.A., Pais, J., Franks, D.G. 2015. Developmental exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters DNA methyltransferase (dnmt) expression in zebrafish (Danio rerio). Toxicology and Applied Pharmacology, 284(2):142-151.

Aluru, N., Karchner, S.I., Franks, D.G., Nacci, D., Champlin, D., Hahn, M.E. 2015. Targeted mutagenesis of 2a and 2b genes in Atlantic Killifish (Fundulus heteroclitus). Aquatic Toxicology 158: 192-201.


Wang, L., Zhang, J., Duan, J., Gao, X., Zhu, W., Lu, X., Yang, L., Zhang, J., Li, G., Ci, W., Li, W., Zhou, Q., Aluru, N., Tang, F., He, C., Huang, X., Liu, J. 2014. Programming and inheritance of parental DNA methylomes in mammals. Cell 157(4): 979-991.

Aluru, N., Jenny, M.J., Hahn, M.E. 2014. Knockdown of a Zebrafish Aryl Hydrocarbon Receptor Repressor (ahrra) Affects Expression of Genes Related to Photoreceptor Development and Hematopoiesis. Toxicological Sciences 139: 381-395.


Aluru, N., Deak, K.L*., Jenny, M.J., Hahn, M.E. 2013. Developmental exposure to valproic acid alters the expression of microRNAs involved in neurodevelopment in zebrafish. Neurotoxicology and Teratology 40:46-58.


Jenny, M.J., Aluru, N., Hahn, M.E. 2012. Effects of short-term exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on microRNA expression in zebrafish embryos. Toxicology and Applied Pharmacology 264: 262-273.

Barkataki, S., Aluru, N., Li, M., Vijayan, M.M., Leatherland, J.F. 2012. Characteristics of ovarian follicle steroidogenesis during vitellogenesis in an asynchronously ovulating stock of rainbow trout Oncorhynchus mykiss. Journal of Fish Biology 80: 741-751.


Shepherd, B., Aluru, N., Vijayan, M.M. 2011. Acute handling disturbance modulates plasma insulin like growth factor binding proteins in Rainbow trout. Domestic Animal Endocrinology 40: 129-139.

Aluru, N., Karchner S.I., Hahn M.E. 2011. Role of DNA methylation of AHR1 and AHR2 promoters in differential sensitivity to PCBs in Atlantic Killifish, Fundulus heteroclitus. Aquatic Toxicology 101: 288-294.

Alsop, D., Aluru, N. 2011. Development of hypothalamus-pituitary-interrenal axis. Encyclopedia of Fish Physiology: From Genome to Environment. A.P. Farrell, Editor, Elsevier. ISBN: 978-0-12-374545-3.


Vijayan, M.M., N. Aluru, Leatherland, J.F. 2010Organismal and cellular stress, in Fish Diseases and Disorders, Volume 2: Non-infectious Disorders, J.F. Leatherland and P.Woo. Editors., CAB International: Oxfordshire, UK. p. 416.

Nikaido, Y., Aluru, N., McGuire, A., Park, Y.J., Vijayan, M.M., Takemura, A. 2010. Effect of cortisol on melatonin production by the pineal organ of tilapia, Oreochromis mossambicusComparative Biochemistry and Physiology A. Molecular and Integrative Physiology 155: 84-90.

Methling, C., Aluru, N., Vijayan, M.M., Steffensen, J.F. 2010. Effect of moderate hypoxia at three acclimation temperatures on stress responses in Atlantic cod with different hemoglobin types. Comparative Biochemistry and Physiology A. Molecular and Integrative Physiology 156: 485-490.

McGuire, A., Aluru, N., Takemura, A., Weil, R., Wilson, J.M., Vijayan, M.M. 2010. Hyperosmotic shock adaptation by cortisol involves upregulation of branchial osmotic stress transcription factor 1 gene expression in Mozambique Tilapia. General and Comparative Endocrinology 165: 321-329.

Aluru, N., Leatherland, J.F., Vijayan, M.M. 2010. Bisphenol A in oocytes leads to growth suppression and altered stress performance in juvenile Rainbow trout. PLoS One 5: e10741.


Aluru, N., Vijayan, M.M. 2009. Stress transcriptomics in fish: A role for genomic cortisol signaling. General and Comparative Endocrinology 164: 142-150


Aluru, N., Vijayan, M.M. 2008. Brain transcriptomics in response to β-naphthoflavone treatment in rainbow trout: the role of aryl hydrocarbon receptor signaling. Aquatic Toxicology 87: 1-12.

Aluru, N., Vijayan, M.M. 2008. Molecular characterization, tissue specific expression and regulation of melanocortin 2 receptor in rainbow trout. Endocrinology 149: 4577-4588.


Park, C.B., Takemura, A., Aluru, N., Park, Y.J., Kim, B.H., Lee, C.H., Lee, Y.D., Moon, T.W., Vijayan, M.M. 2007. Tissue-specific suppression of estrogen, androgen and glucocorticoid receptor gene expression in feral vitellogenic male Mozambique tilapia. Chemosphere 69: 32-40.

Moran. P.W., Aluru,N., Black, R. W., Vijayan, M.M. 2007. Tissue contaminants and associated transcriptional response in trout liver from remote high elevation lakes of Western Washington. Environmental Science and Technology 41: 6591-6597.

Aluru, N., Vijayan, M.M. 2007. Hepatic transcriptome response to glucocorticoid receptor activation in rainbow trout. Physiological Genomics 31: 483-491.


Vijayan, M.M., Aluru, N., Maule, A.G., Jorgensen, E.H. 2006. Fasting augments PCB impact on liver metabolism in anadromous Arctic charr. Toxicological Sciences 91: 431-439.

Jorgensen, E.H., Vijayan, M.M., Killie, J.E.A., Aluru, N., Aas-Hansen, O., Maule, A.G. 2006. Toxicokinetics and effects of PCB in Arctic fish: A review of studies on Arctic charr. J. Toxicology and Environmental Health, Part A. 69: 37-52.

Aluru, N., Vijayan, M.M. 2006. Aryl hydrocarbon receptor activation impairs cortisol response to stress in rainbow trout by disrupting the rate-limiting steps in steroidogenesis. Endocrinology 147: 1895-1903.

Aluru, N., Vijayan, M.M. 2006. Resveratrol affects CYP1A expression in rainbow trout hepatocytes. Aquatic Toxicology 77: 291-297.


Cara, J.B., Aluru, N., Moyano, F.J., Vijayan, M.M. 2005. Food-deprivation induces HSP70 and HSP90 protein expression in larval gilthead sea bream and rainbow trout. Comparative Biochemistry Physiolology B. Biochemistry and Molecular Biology 142: 426-431.

Aluru, N., Vuori, K., Vijayan, M.M. 2005. Modulation of Ah receptor and CYP1A1 expression by alpha-naphthoflavone in rainbow trout hepatocytes. Comparative Biochemistry Physiology C Toxicology Pharmacology 141: 40-49.

Aluru, N., Renaud, R., Leatherland, J.F., Vijayan, M.M. 2005. Ah Receptor-mediated impairment of interrenal steroidogenesis involves StAR protein and P450scc gene attenuation in rainbow trout. Toxicological Sciences 84: 260-269.


Aluru, N. and M.M. Vijayan. 2004. beta-Naphthoflavone disrupts cortisol production and liver glucocorticoid responsiveness in rainbow troutAquat Toxicol, 67(3): 273-285.

Aluru, N., Jorgensen, E.H., Maule, A.G., Vijayan, M.M. 2004. PCB disruption of the hypothalamus-pituitary-interrenal axis involves brain glucocorticoid receptor downregulation in anadromous Arctic charr. American Journal of Physiology Integrative Comparative Physiology 287: R787-R793.


Jorgensen, E.H., Vijayan, M.M., Aluru, N., Maule, A.G. 2002. Fasting modifies Aroclor 1254 impact on plasma cortisol, glucose and lactate responses to a handling disturbance in Arctic charr. Comparative Biochemistry Physiolology C Toxicology Pharmacology 132: 235-245.